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Substance Comparison
Bupropion lasts considerably longer at around 24 hours, while α-PVP clocks in at roughly 4.5 hours. α-PVP stands out with markedly stronger addiction risk. In terms of stimulation, α-PVP scores notably higher. In terms of body load, α-PVP scores notably higher.
Despite belonging to different classes, these substances share receptor activity at DAT and NET, which may produce overlapping effects.
Insights
α-PVP has significantly higher addiction risk
α-PVP has notably higher stimulation
α-PVP has notably higher body load
Bupropion has somewhat higher sedation
| α-PVP | Bupropion | |
|---|---|---|
| Class | Stimulanzien | Antidepressiva |
| Risk Level | high | low |
| Mechanisms | DAT-Inhibitor (potent), NET-Inhibitor | DAT-Inhibitor, NET-Inhibitor |
| Receptors | DAT, NET | DAT, NET |
| Effects | Gesteigerte Wachheit und Konzentration, Erhöhter Antrieb und Motivation, Euphorie und gesteigertes Selbstvertrauen, Verminderte Müdigkeit, Gesteigerte körperliche Leistungsfähigkeit | Antidepressiv, Stimmungsaufhellend, Appetithemmend, Energiesteigernd, Konzentrationsfördernd |
| Evidence | unknown | unknown |
Bupropion wirkt als Hemmer der Wiederaufnahme von Dopamin und Noradrenalin, was zu einer Erhöhung der Verfügbarkeit dieser Neurotransmitter im synaptischen Spalt führt.
Safer-use data available on substance page
Safer-use data available on substance page
Evidence: unknown · Sources: 4
Evidence: unknown · Sources: 3