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Substance Comparison
Ibogain stands out with markedly stronger psychedelic depth. Alkohol / Ethanol stands out with markedly stronger sedation. In terms of empathy & warmth, Ibogain scores notably higher. In terms of dissociation, Ibogain scores notably higher.
Despite belonging to different classes, these substances share receptor activity at NMDA, which may produce overlapping effects.
Ibogain has significantly higher psychedelic depth
Alkohol / Ethanol has significantly higher sedation
Ibogain has notably higher empathy & warmth
Ibogain has notably higher dissociation
| Alkohol / Ethanol | Ibogain | |
|---|---|---|
| Class | Depressiva | Psychedelika |
| Risk Level | high | high |
| Mechanisms | GABA-A-Potenzierung, NMDA-Antagonismus, Endorphinfreisetzung | κ-Opioid-Agonist, NMDA-Antagonist, SERT-Inhibitor, σ-Rezeptor-Agonist |
| Receptors | GABA-A, NMDA | κ-Opioid, NMDA, SERT, σ-1 |
| Effects | — | — |
| Evidence | — | — |
No harm reduction data available
No harm reduction data available
Evidence: not assessed · Sources: 2
Evidence: not assessed · Sources: 2