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Valproic acid

Valproic acid is an anticonvulsant and mood stabilizer that primarily acts by increasing GABA levels in the brain. It is used for the treatment of epilepsy, bipolar disorders, and migraine prophylaxis. The substance affects several neuronal channels and neurotransmitter systems, contributing to its anticonvulsant and mood-stabilizing effects. Valproic acid is associated with a moderate risk, particularly due to potential teratogenic effects and hepatotoxic side effects.

Antikonvulsiva
Depressiva
Antidepressiva
GABA-A-Rezeptoren
Natriumkanäle

Mechanism of Action

  • GABA-A agonist
  • Sodium channel blocker

Names / Identifiers

IUPAC: Valproic acid

VALPROIC ACID
2-Propylpentanoic acid
99-66-1
2-Propylvaleric acid
Dipropylacetic acid
Depakene
Depakine
Mylproin
Di-n-propylacetic acid
Propylvaleric acid

Mechanism of Action

Valproinsäure wirkt hauptsächlich durch die Erhöhung der GABA-Spiegel im Gehirn, was zu einer Hemmung der neuronalen Erregung führt.

Effects

Antikonvulsiv
Stimmungsstabilisierend
Neuroprotektiv
Angstlösend
Schmerzlindern

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak4-6 hours
NotesEffect may vary depending on individual response.
Onset1-4 hours
Total12-24 hours
After EffectsFatigue, dizziness

Risks & Warnings

Warnings

  • Severe liver disease
  • Pregnancy without medical supervision

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen Schwindel, Müdigkeit und gastrointestinale Beschwerden.

Safer Use

  • Conduct regular medical check-ups.
  • Watch for signs of liver problems.

Harm reduction tips do not replace medical advice.

Known Interactions

  • May interact with other anticonvulsants.
  • Interactions with certain antidepressants possible.

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesValproinsäure ist in vielen Ländern als Medikament zugelassen, insbesondere zur Behandlung von Epilepsie und bipolaren Störungen.

Not legal advice. Status may change.