Synapedia

Translated automatically – community improvements welcome.

Perphenazine

Perphenazine is a typical antipsychotic from the group of phenothiazines, which primarily acts through dopamine D2 receptor antagonism. It is used for the treatment of schizophrenia and other psychotic disorders. Side effects may include extrapyramidal symptoms and sedation. The substance also affects serotonergic and adrenergic receptors, leading to a complex effect profile.

Antipsychotika
Antidepressiva
Dopamin-D2-Rezeptoren

Mechanism of Action

  • D2 receptor antagonist

Names / Identifiers

IUPAC: Perphenazine

perphenazine
58-39-9
Trilafon
Perphenazin
Perfenazine
Etaperazine
Chlorpiprazine
Etaperazin
Ethaperazine
Fentazin

Mechanism of Action

Perphenazin wirkt hauptsächlich als Antagonist an Dopamin-D2-Rezeptoren, was zu einer Reduktion von psychotischen Symptomen führt.

Effects

Antipsychotisch
Sedierend
Anxiolytisch
Antiemetisch
Extrapyramidale Symptome
Gewichtszunahme
Hypotension
Anticholinerg
Sedation

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak4-6 hours
NotesEffect may vary depending on dosage and individual sensitivity.
Onset1-2 hours
Total24 hours
After EffectsVariable

Risks & Warnings

Warnings

  • Known hypersensitivity to perphenazine
  • Severe liver disease

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen extrapyramidale Symptome und Sedierung.

Safer Use

  • Regular medical monitoring
  • Start at a low dose
  • Watch for signs of side effects

Harm reduction tips do not replace medical advice.

Known Interactions

  • Increased sedative effect with alcohol
  • Interactions with other antipsychotics

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesIn vielen Ländern ist Perphenazin nur auf Rezept erhältlich.

Not legal advice. Status may change.