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7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one
Norflurazepam is an active metabolite of flurazepam and acts as a benzodiazepine with anxiolytic, sedative, and muscle relaxant properties through modulation of the GABA-A receptor. It has a long half-life, which can lead to prolonged effects. The substance is being pharmacologically investigated for the treatment of anxiety disorders and sleep disturbances. Due to its potential for dependence and sedative effects, caution is advised.
Translation in progress
This section is currently being translated. Content will be available soon.
View German version →Receptor Targets
Mechanism of Action
Norflurazepam acts through the following pharmacological mechanisms:
Designations
IUPAC: 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one
Receptor Profile
Der GABA-A-Rezeptor ist ein ligandengesteuerter Chloridkanal und der wichtigste inhibitorische Rezeptor im zentralen Nervensystem. Er besitzt multiple allosterische Bindungsstellen für verschiedene Substanzklassen.
Synapedia Evidence
Effects & Pharmacology — Translation in progress
This section is being translated. Content is available in German.
View in German →Total duration 12-24 hours
Peak
2-4 hours
Onset
30-60 minutes
Total duration
12-24 hours
After effects
Fatigue, drowsiness
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Summary
Mögliche Abhängigkeit und Toleranzentwicklung bei längerem Gebrauch.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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