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Meperidine (Pethidine) is a synthetic opioid primarily used as an analgesic. It acts primarily as an agonist at the μ-opioid receptor and possesses analgesic properties. Due to its potential for dependence and side effects such as seizures, careful application is required. Meperidine is structurally distinct from other opioids due to its phenylpiperidine structure.
Translation in progress
The German version has more complete content. This English page is being expanded; safety-critical risk and interaction sections may still appear while translation continues.
Receptor Targets
Mechanism of Action
Meperidine (Pethidine) acts through the following pharmacological mechanisms:
Designations
IUPAC: Meperidine (Pethidine)
Synapedia Evidence
Effects & Pharmacology translation in progress
English prose is being expanded. The German version currently has more detail.
Total duration 2-4 hours
Peak
1-2 hours
Onset
10-15 minutes (IV), 30-60 minutes (oral)
Total duration
2-4 hours
After effects
1-2 hours
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Summary
Hohe Abhängigkeitspotenzial und Nebenwirkungen wie Krampfanfälle.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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