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Meperidine (Pethidine)

Meperidine (Pethidine) is a synthetic opioid primarily used as an analgesic. It acts primarily as an agonist at the μ-opioid receptor and possesses analgesic properties. Due to its potential for dependence and side effects such as seizures, careful application is required. Meperidine is structurally distinct from other opioids due to its phenylpiperidine structure.

Opioid

Mechanism of Action

  • μ-opioid receptor agonist
Detailed mechanism of action

Names / Identifiers

IUPAC: Meperidine (Pethidine)

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak1-2 hours
NotesDuration of action may vary depending on dose and route of administration.
Onset10-15 minutes (IV), 30-60 minutes (oral)
Total2-4 hours
After Effects1-2 hours

Risks & Warnings

Warnings

  • Respiratory depression
  • Pregnancy
  • severe liver or kidney disease

Known Risks

  • high
  • Hohe Abhängigkeitspotenzial und Nebenwirkungen wie Krampfanfälle.

Safer Use

  • Start at a low dose
  • Avoid polydrug use with other CNS depressants

Harm reduction tips do not replace medical advice.

Known Interactions

  • Benzodiazepines
  • Alcohol
  • other opioids

This list is not exhaustive. Interactions can have unpredictable effects.