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Levomethadone

Levomethadone is the active enantiomer of methadone and acts as a strong synthetic opioid, primarily used as an analgesic and in substitution therapy. It selectively binds to μ-opioid receptors and exhibits a long duration of action. Due to its potential for dependence and the risks of overdose, careful handling is required.

Opioide

Mechanism of Action

  • μ-opioid receptor agonist

Names / Identifiers

IUPAC: Levomethadone

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak2-4 hours
NotesThe duration of action may vary depending on dose and individual metabolism.
Onset30-60 minutes
Total24-36 hours
After EffectsVariable, may last several hours.

Risks & Warnings

Warnings

  • Respiratory diseases
  • severe liver or kidney diseases
  • Pregnancy

Known Risks

  • high
  • Hohe Abhängigkeitspotenzial und Risiko für Überdosierung.

Safer Use

  • Start at a low dose
  • Avoid polydrug use with other depressant substances
  • Regular monitoring of the dose

Harm reduction tips do not replace medical advice.

Known Interactions

  • Benzodiazepines
  • Alcohol
  • other opioids

This list is not exhaustive. Interactions can have unpredictable effects.