Laden…
(6R)-6-(dimethylamino)-4,4-diphenyl-heptan-3-one
Levomethadone is the active enantiomer of methadone and acts as a strong synthetic opioid, primarily used as an analgesic and in substitution therapy. It selectively binds to μ-opioid receptors and exhibits a long duration of action. Due to its potential for dependence and the risks of overdose, careful handling is required.
Translation in progress
The German version has more complete content. This English page is being expanded; safety-critical risk and interaction sections may still appear while translation continues.
Receptor Targets
Mechanism of Action
Levomethadone acts through the following pharmacological mechanisms:
Designations
IUPAC: (6R)-6-(dimethylamino)-4,4-diphenyl-heptan-3-one
Synapedia Evidence
Effects & Pharmacology translation in progress
English prose is being expanded. The German version currently has more detail.
Total duration 24-36 hours
Peak
2-4 hours
Onset
30-60 minutes
Total duration
24-36 hours
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Summary
Hohe Abhängigkeitspotenzial und Risiko für Überdosierung.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
Share a report, observation, or question about this substance. Entries are reviewed before publication and marked as unverified community signals.
These entries are submitted by users and are not verified. They may contain subjective experiences, observations, source leads, or corrections. They do not replace scientific data and are not consumption advice.
The signal hub collects approved risk signals, experience reports and source leads by relevance.