Synapedia

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Brotizolam

Brotizolam is a short-acting benzodiazepine with sedative, anxiolytic, and muscle-relaxing properties. It acts as a positive allosteric modulator at the GABA-A receptor, which enhances inhibitory neurotransmission in the central nervous system. Due to its pharmacological profile, it is primarily used for the treatment of sleep disorders. The risk of dependence and withdrawal symptoms is increased with prolonged use.

Benzodiazepine

Mechanism of Action

  • positive allosteric modulator of GABA-A

Names / Identifiers

IUPAC: Brotizolam

Mechanism of Action

Brotizolam wirkt als Agonist am GABA-A-Rezeptor, was zu einer verstärkten Hemmung der neuronalen Aktivität im zentralen Nervensystem führt.

Effects

Sedierung
Anxiolyse
Muskelrelaxation
Amnesie
Antikonvulsive Wirkung
Euphorie

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start with a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak1-2 hours
NotesDuration of action may vary depending on individual metabolism.
Onset30-60 minutes
Total6-8 hours
After Effects2-4 hours

Risks & Warnings

Warnings

  • Pregnancy
  • Sleep apnea
  • severe respiratory diseases

Known Risks

  • medium
  • Mögliche Abhängigkeit und Toleranzentwicklung bei längerem Gebrauch.

Safer Use

  • Start with a low dose.
  • Avoid alcohol and other sedating substances.

Harm reduction tips do not replace medical advice.

Known Interactions

  • Alcohol
  • Opioids
  • other benzodiazepines

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USNicht zugelassen
NotesIn Deutschland und Österreich ist Brotizolam verschreibungspflichtig. In der Schweiz ebenfalls, während es in den USA nicht zugelassen ist.

Not legal advice. Status may change.

Entdecken

Gemeinsame Wirkungsmuster

Wirkungen, die Brotizolam mit verwandten Substanzen teilt.

euphorie
auch beiKratom, Amphetamin, DMT+3 weitere
sedierung
auch beiKratom