High Risk: Increased cardiovascular strain and cocaethylene formation
When cocaine and alcohol are used together the body forms cocaethylene, a metabolite that is longer-acting and places additional strain on the cardiovascular system. The combination is associated with increased heart rate and blood pressure and a heightened risk of cardiovascular events compared with either substance alone.
Mechanism data is language-neutral pharmacological notation.
This page is based on curated pharmacological data and/or community signals. It is intended for scientific education and harm reduction only. It does not replace professional medical advice. Not all interactions are covered — always consult a healthcare professional when in doubt. In emergencies, call your local emergency number.