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Substance Comparison
α-PHP stands out with markedly stronger stimulation. Alkohol / Ethanol stands out with markedly stronger sedation. In terms of dissociation, Alkohol / Ethanol scores notably higher. In terms of body load, α-PHP scores notably higher.
Comparing these substances helps illustrate the diversity of psychoactive pharmacology and their distinct risk profiles.
α-PHP has significantly higher stimulation
Alkohol / Ethanol has significantly higher sedation
Alkohol / Ethanol has notably higher dissociation
α-PHP has notably higher body load
| Alkohol / Ethanol | α-PHP | |
|---|---|---|
| Class | Depressiva | Stimulanzien |
| Risk Level | high | high |
| Mechanisms | GABA-A-Potenzierung, NMDA-Antagonismus, Endorphinfreisetzung | DAT-Inhibitor, NET-Inhibitor |
| Receptors | GABA-A, NMDA | DAT, NET |
| Effects | — | Gesteigerte Wachheit und Konzentration, Erhöhter Antrieb und Motivation, Euphorie und gesteigertes Selbstvertrauen, Verminderte Müdigkeit, Gesteigerte körperliche Leistungsfähigkeit |
| Evidence | — | unknown |
Alpha-Pyrrolidinohexiophenone wirkt hauptsächlich als Hemmer der Wiederaufnahme von Dopamin, Noradrenalin und Serotonin, was zu einer erhöhten Verfügbarkeit dieser Neurotransmitter im synaptischen Spalt führt.
Harm Reduction
No harm reduction data available
Safer-use data available on substance page
Evidence: not assessed · Sources: 2
Evidence: unknown · Sources: 3