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Harmaline

Harmaline is a naturally occurring beta-carboline that primarily acts as a reversible MAO-A inhibitor, thereby inhibiting the breakdown of monoamines in the brain. It possesses psychedelic properties that are mediated by partial agonism at serotonin receptors. Harmaline is found in various plant species and is used in traditional contexts. Due to its MAO-inhibiting effect, interactions with other substances may occur, which necessitates caution.

Psychedelika

Mechanism of Action

  • 5-HT2A agonist
  • MAO-A inhibitor
Detailed mechanism of action

Names / Identifiers

IUPAC: Harmaline

Dosage

Safety NoteIndividual variation, start with a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak1-2 hours
NotesDuration may vary depending on dose and individual reaction.
Onset30-60 minutes
Total4-8 hours
After Effects2-4 hours

Risks & Warnings

Warnings

  • Pregnancy
  • Cardiovascular diseases

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen Übelkeit, Schwindel und Angstzustände.

Safer Use

  • Start with a low dose.
  • Avoid simultaneous use of MAO inhibitors or serotonergic substances.

Harm reduction tips do not replace medical advice.

Known Interactions

  • Serotonergic medications
  • MAO inhibitors

This list is not exhaustive. Interactions can have unpredictable effects.