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1-(4-fluorophenyl)-4-[4-(2-methoxyphenyl)piperazino]butan-1-one
Fluanisone is a typical neuroleptic from the group of butyrophenones, primarily used as an antipsychotic and sedative. It mainly acts through the blockade of dopamine D2 receptors and additionally exhibits alpha-adrenergic antagonism properties. The substance is often used in combination with other sedatives to achieve a calming effect. Side effects may include extrapyramidal symptoms and cardiovascular effects.
Translation in progress
The German version has more complete content. This English page is being expanded; safety-critical risk and interaction sections may still appear while translation continues.
Receptor Targets
Mechanism of Action
Designations
IUPAC: 1-(4-fluorophenyl)-4-[4-(2-methoxyphenyl)piperazino]butan-1-one
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Receptor Profile
Der D2-Rezeptor ist ein Gi-gekoppelter Dopaminrezeptor mit hoher Dichte im Striatum. Er ist ein wichtiges Ziel für Antipsychotika und moduliert motorische Funktionen sowie Belohnungsverarbeitung.
Der α1-adrenerge Rezeptor ist ein Gq/11-gekoppelter GPCR, der Vasokonstriktion, Mydriasis und glatte Muskelkontraktion vermittelt. Er spielt eine zentrale Rolle bei der sympathischen Kreislaufregulation.
Der α2-adrenerge Rezeptor ist ein Gi/Go-gekoppelter GPCR, der als präsynaptischer Autorezeptor die Noradrenalinfreisetzung hemmt. Er vermittelt Sedierung, Analgesie und Blutdrucksenkung.
Synapedia Evidence
Effects & Pharmacology translation in progress
English prose is being expanded. The German version currently has more detail.
Total duration 12-24 hours
Peak
2-4 hours
Onset
30-60 minutes
Total duration
12-24 hours
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Summary
Mögliche Nebenwirkungen umfassen Sedierung, extrapyramidale Symptome und kardiovaskuläre Effekte.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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