Translated automatically – community improvements welcome.
Doxepin
Doxepin is a tricyclic antidepressant with sedative properties that primarily acts by inhibiting the reuptake of serotonin and norepinephrine. It also possesses antagonistic effects at histamine and muscarinic acetylcholine receptors, leading to sedative and anticholinergic effects. Doxepin is therapeutically used for the treatment of depression and sleep disorders. The risk of side effects is moderate, particularly anticholinergic effects and sedation should be noted.
Mechanism of Action
- NET inhibitor
- SERT inhibitor
Names / Identifiers
IUPAC: Doxepin
Mechanism of Action
Doxepin wirkt hauptsächlich durch die Hemmung der Wiederaufnahme von Serotonin und Noradrenalin, was zu einer Erhöhung der Verfügbarkeit dieser Neurotransmitter im synaptischen Spalt führt.
Dosage
Individual sensitivity varies. Not a dosage recommendation.
Duration
Risks & Warnings
Warnings
- Pregnancy
- Breastfeeding
- Glaucoma
Known Risks
- medium
- Mögliche Nebenwirkungen umfassen Schläfrigkeit, Mundtrockenheit und Verwirrtheit.
Safer Use
- Start at a low dose
- Avoid alcohol
- Regular medical monitoring
Harm reduction tips do not replace medical advice.
Known Interactions
- MAO inhibitors
- Benzodiazepines
- Alcohol
This list is not exhaustive. Interactions can have unpredictable effects.