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N-[2-(5-methoxy-1-benzofuran-3-yl)ethyl]-N-propan-2-ylpropan-2-amine
5-MeO-DiBF is a psychedelic benzofuran derivative that primarily acts as a 5-HT2A agonist. It exhibits effects on serotonin receptors, which are responsible for its hallucinogenic properties. The substance is considered a potential tool for investigating serotonergic systems in research.
Translation in progress
The German version has more complete content. This English page is being expanded; safety-critical risk and interaction sections may still appear while translation continues.
Receptor Targets
Mechanism of Action
Designations
IUPAC: N-[2-(5-methoxy-1-benzofuran-3-yl)ethyl]-N-propan-2-ylpropan-2-amine
Receptor Profile
Der 5-HT2A-Rezeptor ist ein Serotonin-Rezeptor der Klasse Gq-gekoppelter GPCRs. Er ist der primäre molekulare Angriffspunkt klassischer Psychedelika und spielt eine Rolle bei Kognition und Wahrnehmung.
Der 5-HT1A-Rezeptor ist ein Gi/Go-gekoppelter Serotoninrezeptor, der als Autorezeptor auf serotonergen Neuronen und als Heterorezeptor in verschiedenen Hirnregionen vorkommt. Er moduliert Angst, Stimmung und Kognition.
Synapedia Evidence
Effects & Pharmacology is partially translated. Some details are still being expanded.
5-MeO-DiBF functions as an agonist at the 5-HT2A receptor, influencing serotonergic signaling pathways.
Known Effects
Individual effects may vary significantly. These are pharmacologically documented effects.
Dosage & Duration translation in progress
English prose is being expanded. The German version currently has more detail.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks & Harm Reduction is partially translated. Some details are still being expanded.
Risks
Summary
Geringes akutes Toxizitätsrisiko bei typischen Dosen. Set und Setting entscheidend — Risiko für angstbesetzte Erfahrungen (Bad Trips), Depersonalisation und in seltenen Fällen anhaltende Wahrnehmungsstörungen (HPPD). Kein physisches Abhängigkeitspotenzial.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interactions translation in progress
English prose is being expanded. Safety-critical structured data may still be shown when available.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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