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Substance Comparison
5-MeO-DMT and Meskalin are both classified as Psychedelika. Available data suggests they share activity at 5-HT2A. 5-MeO-DMT is commonly associated with a higher risk profile compared to Meskalin.
Both substances belong to the Psychedelika class, making this a common comparison for understanding differences within the same pharmacological family.
| 5-MeO-DMT | Meskalin | |
|---|---|---|
| Class | Psychedelika | Psychedelika |
| Risk Level | high | moderate |
| Mechanisms | 5-HT2A-Agonist, 5-HT1A-Agonist, MAO-Substrat | 5-HT2A-Agonist |
| Receptors | 5-HT2A, 5-HT1A, MAO-A | 5-HT2A, 5-HT2C |
| Effects | Vollständige oder teilweise Ego-Auflösung, Tiefgreifende mystische oder nicht-duale Erfahrungen, Intensives Körpergefühl und Vibration, Zeitauflösung — Gefühl der Zeitlosigkeit, Überwältigung und vorübergehende Angst | — |
| Evidence |
5-Methoxy-DMT wirkt hauptsächlich als Agonist an Serotoninrezeptoren, insbesondere am 5-HT2A-Rezeptor, was zu seinen psychedelischen Effekten führt.
Safer-use data available on substance page
No harm reduction data available
Evidence: unknown · Sources: 2
Evidence: not assessed · Sources: 2
| unknown |
| — |