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Substance Comparison
DMT and Ibogain are both classified as Psychedelika. DMT is commonly associated with a moderate risk profile compared to Ibogain.
Both substances belong to the Psychedelika class, making this a common comparison for understanding differences within the same pharmacological family.
| DMT | Ibogain | |
|---|---|---|
| Class | Psychedelika | Psychedelika |
| Risk Level | moderate | high |
| Mechanisms | 5-HT2A-Agonist, Sigma-1-Agonist | κ-Opioid-Agonist, NMDA-Antagonist, SERT-Inhibitor, σ-Rezeptor-Agonist |
| Receptors | 5-HT2A, 5-HT1A, Sigma-1 | κ-Opioid, NMDA, SERT, σ-1 |
| Effects | Sofortiger Wirkungseintritt: nach Sekunden vollständige Loslösung von der Umgebung, Breakthrough-Erfahrung: vollständig andere Dimensionen oder Realitäten bei hoher Dosis, Begegnungen mit geometrischen Strukturen, Fraktalen und „Entitäten", Extrem intensive visuelle Halluzinationen, leuchtende Farben und Muster, Vollständige Ich-Auflösung und Raum-Zeit-Kollaps |
DMT wirkt hauptsächlich als Agonist an Serotoninrezeptoren, insbesondere dem 5-HT2A-Rezeptor, was zu veränderten Bewusstseinszuständen und Halluzinationen führt.
Safer-use data available on substance page
No harm reduction data available
Evidence: unknown · Sources: 2
Evidence: not assessed · Sources: 2
| — |
| Evidence | unknown | — |