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Evidence-based guidance for risk minimisation
Harm Reduction
The safest option is always abstinence. If substances are used regardless, evidence-based precautions can meaningfully reduce risk. The guidance below is informational — it does not make substance use safe.
Safer use guidance is being compiled
Detailed safer use information for Sub%3a5-MeO-DMT is not yet available in English. General harm reduction principles apply: ensure a safe and comfortable setting, avoid combining substances, and have a trusted person present. For substance-specific guidance, consult PsychonautWiki.
Disclaimer: This information is provided for educational purposes only and does not constitute medical advice. It does not make substance use safe. If you have concerns about substance use, please consult a qualified healthcare professional or contact a local drug support service.