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Droperidol

Droperidol is a butyrophenone derivative with predominantly dopamine antagonist effects, primarily used as an antipsychotic and antiemetic. It acts primarily by blocking dopamine D2 receptors and has sedative as well as antiemetic effects. Due to its pharmacological profile, it can cause side effects such as extrapyramidal symptoms and QT prolongations. The substance is mainly used in clinical practice for the treatment of nausea and psychotic states.

Depressiva
Depressiva
Dopamin-D2-Rezeptoren

Mechanism of Action

  • Dopamin-D2 antagonist

Names / Identifiers

IUPAC: Droperidol

Mechanism of Action

Droperidol wirkt hauptsächlich durch die Blockade von Dopamin-D2-Rezeptoren im zentralen Nervensystem, was zu seinen sedierenden und antiemetischen Effekten führt.

Effects

Sedierung
Antiemetikum
Dopaminantagonismus
Reduktion von Übelkeit
Psychotische Symptome lindern
Extrapyramidale Symptome
QT-Verlängerung

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak30-60 minutes
NotesThe duration of action may vary depending on dose and individual response.
Onset5-10 minutes
Total2-4 hours
After EffectsVariable

Risks & Warnings

Warnings

  • Hypersensitivity to butyrophenones
  • Parkinson's disease

Known Risks

  • medium
  • Droperidol kann sedierende Effekte und potenzielle Nebenwirkungen wie Hypotonie verursachen.

Safer Use

  • Start at a low dose
  • Monitoring of vital signs recommended

Harm reduction tips do not replace medical advice.

Known Interactions

  • Benzodiazepines
  • Alcohol
  • Opioids

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesDroperidol ist in vielen Ländern aufgrund seiner Wirkungen und Nebenwirkungen reguliert.

Not legal advice. Status may change.

Entdecken

Ähnliche Substanzen

Basierend auf Substanzklasse, Rezeptoren, Wirkmechanismen und Wirkprofil.

Gemeinsame Wirkungsmuster

Wirkungen, die Droperidol mit verwandten Substanzen teilt.

sedierung
auch beiKratom