Synapedia

Translated automatically – community improvements welcome.

Cocaine

Cocaine is a powerful stimulant that primarily acts by inhibiting the reuptake of dopamine, norepinephrine, and serotonin. It leads to increased alertness, euphoria, and heightened energy, but carries a high risk of addiction and cardiovascular complications. Cocaine is also used as a local anesthetic, and its neurotoxic and cardiotoxic effects are well documented.

Stimulanzien

Mechanism of Action

  • DAT inhibitor
  • NET inhibitor
  • SERT inhibitor

Names / Identifiers

IUPAC: Cocaine

Mechanism of Action

Kokain wirkt als Hemmer der Wiederaufnahme von Dopamin, Serotonin und Noradrenalin, was zu einer erhöhten Konzentration dieser Neurotransmitter im synaptischen Spalt führt.

Dosage

Safety NoteIndividual variation, start with a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak15-30 minutes
NotesEffects may vary depending on the method of consumption.
Onset1-5 minutes
Total30-90 minutes
After Effects1-2 hours

Risks & Warnings

Warnings

  • Cardiovascular diseases
  • Pregnancy
  • Mental disorders

Known Risks

  • high
  • Hohe Abhängigkeitspotential und kardiovaskuläre Risiken.

Safer Use

  • Start with a low dose
  • Avoid polydrug use
  • Take regular breaks

Harm reduction tips do not replace medical advice.

Known Interactions

  • Alcohol
  • Benzodiazepines
  • Antidepressants

This list is not exhaustive. Interactions can have unpredictable effects.

Known Interactions

Bildung von Cocaethylen: Erhöhte Kardiotoxizität

Alkohol / Ethanol
High