Translated automatically – community improvements welcome.
Dextromethorphan
Dextromethorphan is a synthetic dissociative primarily used as a cough suppressant. It acts mainly as an NMDA receptor antagonist and additionally affects serotonergic systems as well as Sigma-1 receptors. Due to its dissociative effects, it is occasionally consumed outside of medical indications. The risks include potential neurotoxic effects and interactions with other serotonergic substances.
Mechanism of Action
- NMDA receptor antagonist
- serotonergic modulation
- Sigma-1 receptor interaction
Names / Identifiers
IUPAC: Dextromethorphan
Mechanism of Action
Dextromethorphan wirkt hauptsächlich als Antagonist am NMDA-Rezeptor und beeinflusst auch serotonerge Systeme, was zu seinen dissoziativen und antitussiven Effekten führt.
Effects
Effects described from scientific sources. Individual experiences vary.
Dosage
Individual sensitivity varies. Not a dosage recommendation.
Duration
Risks & Warnings
Warnings
- Pregnancy
- Liver diseases
- Cardiovascular diseases
Known Risks
- medium
- Mögliche Nebenwirkungen umfassen Schwindel, Übelkeit und dissoziative Effekte. Hohe Dosen können zu schwerwiegenden gesundheitlichen Problemen führen.
Safer Use
- Start with a low dose.
- Do not combine with other drugs.
- Consume in a safe environment.
Harm reduction tips do not replace medical advice.
Known Interactions
- MAO inhibitors
- Serotonin reuptake inhibitors
This list is not exhaustive. Interactions can have unpredictable effects.
Legal Status
Not legal advice. Status may change.