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7-chloro-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one

Desmethyldiazepam (Nordazepam) is an active metabolite of Diazepam and other benzodiazepines. It acts as a positive allosteric modulator at the GABA-A receptor and possesses anxiolytic, sedative, and muscle relaxant properties. Due to its long half-life, it can accumulate in the body, increasing the risk of side effects and dependence.

Benzodiazepine

Mechanism of Action

  • GABA-A positive allosteric modulator
Detailed mechanism of action

Names / Identifiers

IUPAC: Desmethyldiazepam (Nordazepam)

Mechanism of Action

Desmethyldiazepam wirkt als Modulator des GABA-A-Rezeptors, wodurch die hemmende Wirkung von GABA im zentralen Nervensystem verstärkt wird.

Effects

anxiolytisch
sedierend
muskelrelaxierend
antikonvulsiv
amnesierend
euphorisierend

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start with a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak1-2 hours
NotesEffects may be influenced by individual factors.
Onset30-60 minutes
Total10-20 hours
After EffectsVariable, may last several hours.

Risks & Warnings

Warnings

  • Severe respiratory diseases
  • Sleep apnea
  • Pregnancy

Known Risks

  • medium
  • Mögliche Abhängigkeit und Toleranzentwicklung bei längerem Gebrauch.

Safer Use

  • Start with a low dose.
  • Do not combine with alcohol or other sedating substances.

Harm reduction tips do not replace medical advice.

Known Interactions

  • Alcohol
  • Opioids
  • Other benzodiazepines

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesIn vielen Ländern ist Desmethyldiazepam als kontrollierte Substanz eingestuft.

Not legal advice. Status may change.