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Delorazepam

Delorazepam is a long-acting benzodiazepine with anxiolytic, hypnotic, and muscle-relaxing properties. It acts by enhancing GABAergic neurotransmission at the GABA-A receptor. Due to its mechanism of action, it is used for the treatment of anxiety disorders and sleep disorders. The substance has a moderate potential for dependence and should therefore be used with caution.

Benzodiazepine

Mechanism of Action

  • GABA-A receptor modulation
Detailed mechanism of action

Names / Identifiers

IUPAC: Delorazepam

Mechanism of Action

Delorazepam wirkt als Agonist am GABA-A-Rezeptor, was zu einer verstärkten Hemmung der neuronalen Aktivität führt.

Dosage

Safety NoteConsider individual variation, start with a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak1-2 hours
NotesDuration of action may vary depending on individual metabolism.
Onset30-60 minutes
Total6-12 hours
After EffectsFatigue, drowsiness

Risks & Warnings

Warnings

  • Pregnancy
  • Severe respiratory diseases
  • Acute glaucoma

Known Risks

  • medium
  • Mögliche Abhängigkeit und Toleranzentwicklung bei längerem Gebrauch.

Safer Use

  • Start with a low dose.
  • Avoid alcohol and other sedating substances.

Harm reduction tips do not replace medical advice.

Known Interactions

  • Alcohol
  • Opioids
  • Other benzodiazepines

This list is not exhaustive. Interactions can have unpredictable effects.