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Cyclobarbital

Cyclobarbital is a barbiturate with sedative and hypnotic effects. It acts by enhancing GABA-A receptor-mediated inhibition in the central nervous system. Due to its mechanism of action, dependence and tolerance development can occur. The substance was previously used as a sleeping aid but has largely been replaced by safer medications due to safety concerns.

Barbiturate

Mechanism of Action

  • GABA-A receptor potentiation
Detailed mechanism of action

Names / Identifiers

IUPAC: Cyclobarbital

Mechanism of Action

Cyclobarbital wirkt als ein GABA-A-Rezeptor-Agonist, der die inhibitorische Wirkung von GABA im zentralen Nervensystem verstärkt.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak2-4 hours
NotesEffects may vary depending on dose and individual response.
Onset30-60 minutes
Total6-8 hours
After Effects1-2 hours

Risks & Warnings

Warnings

  • Pregnancy
  • Respiratory diseases
  • Liver diseases

Known Risks

  • medium
  • Kann zu Abhängigkeit und Toleranz führen. Überdosierung kann lebensbedrohlich sein.

Safer Use

  • Start at a low dose.
  • Avoid polydrug use with other depressant substances.

Harm reduction tips do not replace medical advice.

Known Interactions

  • Alcohol
  • Benzodiazepines
  • Opioids

This list is not exhaustive. Interactions can have unpredictable effects.