Synapedia

Translated automatically – community improvements welcome.

3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-…

Clomipramine is a tricyclic antidepressant that primarily works by inhibiting the reuptake of serotonin and norepinephrine. It is mainly used for the treatment of obsessive-compulsive disorders and depression. Side effects may include anticholinergic effects and sedation. The substance affects several neurotransmitter systems and has a moderate risk profile in therapeutic use.

Antidepressiva

Mechanism of Action

  • NET inhibitor
  • SERT inhibitor

Names / Identifiers

IUPAC: Clomipramine

Mechanism of Action

Clomipramin wirkt hauptsächlich als Hemmer der Wiederaufnahme von Serotonin und Noradrenalin, was zu einer Erhöhung der Verfügbarkeit dieser Neurotransmitter im synaptischen Spalt führt.

Effects

Antidepressiv
Angstlösend
Sedierend
Anticholinerg
Stimmungsaufhellend
Kognitive Beeinträchtigung
Appetitzügelnd
Schlafanstoßend

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteConsider individual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak4-6 weeks
NotesSlow dose adjustment recommended.
Onset1-3 weeks
Total24 hours
After EffectsVariable

Risks & Warnings

Warnings

  • Acute myocardial infarction
  • Pregnancy
  • Lactation

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen anticholinerge Effekte und Sedierung.

Safer Use

  • Regular medical monitoring
  • Avoidance of alcohol
  • Inform about possible interactions

Harm reduction tips do not replace medical advice.

Known Interactions

  • MAO inhibitors
  • other antidepressants
  • alcohol

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesClomipramin ist in vielen Ländern als verschreibungspflichtiges Medikament eingestuft.

Not legal advice. Status may change.