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Clobazam

Clobazam is a benzodiazepine primarily used as an anxiolytic and anticonvulsant. It acts by enhancing GABAergic inhibition in the central nervous system, leading to sedative and muscle-relaxing effects. Due to its mechanism of action, Clobazam can be addictive and should therefore be used with caution.

Benzodiazepine

Mechanism of Action

  • GABA-A receptor positive allosteric modulator
Detailed mechanism of action

Names / Identifiers

IUPAC: Clobazam

Mechanism of Action

Clobazam wirkt als Modulator des GABA-A-Rezeptors, indem es die Wirkung des Neurotransmitters GABA verstärkt, was zu einer sedierenden und anxiolytischen Wirkung führt.

Effects

sedierend
anxiolytisch
muskelrelaxierend
antikonvulsiv
amnesierend

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak1-2 hours
NotesDuration of action may vary depending on dose and individual metabolism.
Onset30-60 minutes
Total6-12 hours
After Effects2-4 hours

Risks & Warnings

Warnings

  • Severe respiratory diseases
  • Acute glaucoma
  • Pregnancy

Known Risks

  • medium
  • Mögliche Abhängigkeit und Toleranzentwicklung bei längerem Gebrauch.

Safer Use

  • Start at a low dose.
  • Do not combine with alcohol or other sedating substances.

Harm reduction tips do not replace medical advice.

Known Interactions

  • Alcohol
  • Opioids
  • Other benzodiazepines

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesClobazam ist in vielen Ländern als verschreibungspflichtiges Medikament eingestuft.

Not legal advice. Status may change.