Synapedia

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Aripiprazole

Aripiprazole is an atypical antipsychotic that primarily acts as a partial dopamine D2 agonist and additionally modulates serotonin receptors. It is used for the treatment of schizophrenia, bipolar disorders, and other mental illnesses. Due to its pharmacological profile, it has a moderate side effect profile, with movement disorders occurring less frequently than with classical antipsychotics. The substance affects various neurotransmitter systems, thereby contributing to mood stabilization and reduction of psychotic symptoms.

Antipsychotika

Mechanism of Action

  • 5-HT1A agonist
  • 5-HT2A antagonist
  • Dopamin-D2 partial agonist

Names / Identifiers

IUPAC: Aripiprazole

Mechanism of Action

Aripiprazol wirkt als partieller Agonist an Dopamin D2-Rezeptoren und als Agonist an Serotonin 5-HT1A-Rezeptoren, was zu einer Modulation der dopaminergen und serotonergen Aktivität im Gehirn führt.

Effects

Antipsychotisch
Stimmungsstabilisierend
Angstlösend
Sedierend
Kognitive Verbesserung

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak3-5 hours
NotesDuration of action may vary depending on individual response.
Onset1-3 hours
Total24 hours
After EffectsVariable

Risks & Warnings

Warnings

  • Allergy to aripiprazole
  • Severe liver disease

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen Gewichtszunahme, Sedierung und extrapyramidale Symptome.

Safer Use

  • Regular medical monitoring
  • Watch for signs of side effects

Harm reduction tips do not replace medical advice.

Known Interactions

  • CYP2D6 inhibitors
  • CYP3A4 inhibitors

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesAripiprazol ist in vielen Ländern als verschreibungspflichtiges Medikament eingestuft.

Not legal advice. Status may change.